Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50019718
Affinity DataKd: 0.350nMAssay Description:Binding affinity to full length BTK (unknown origin) assessed as dissociation constant measured at 37 degree C by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 0.860nMAssay Description:Binding affinity to full length BTK (unknown origin) assessed as dissociation constant measured at 37 degree C by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 2.30nMAssay Description:Binding affinity to full length BTK (unknown origin) assessed as dissociation constant measured at 37 degree C by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of CRBN in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of BTK in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 107nMAssay Description:Inhibition of CRBN in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 107nMAssay Description:Binding affinity to full length BTK (unknown origin) assessed as dissociation constant measured at 37 degree C by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 320nMAssay Description:Inhibition of BTK in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of BTK in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CRBN in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CRBN in HEK293 cells using NanoGlo substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
