Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50020418
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50629795(CHEMBL4635204)
Affinity DataEC50:  0.720nMAssay Description:Inhibition of PD-I/PD-L2 interaction (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50629795(CHEMBL4635204)
Affinity DataEC50:  0.410nMAssay Description:Inhibition of PD-I/PD-L2 interaction (unknown origin) expressed in human MDA-MB-23 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataKd:  366nMAssay Description:Binding affinity to CM5 sensor chip immobilized human recombinant extracellular domain PD-L1 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataKd:  4.95E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human PD-L1 ectodomain (18 to 239 residues) assessed as dissociation constant by SPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM575481(US11459339, Example 1 | N,N′-(2,2′-dim...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Fc-fused recombinant human PD-I/His-tagged recombinant human PD-L1 interaction incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50629797(CHEMBL5403219)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM363277((2S,4S)-1-(5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM363193(US9850225, Example 1122 | (R)-2-(2-(3-cyanobenzylo...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50405453(CHEMBL5271309)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin) incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human PD-1 (33 to 150 residues)/recombinant human PD-L1 (18 to 134 residues) expressed Escherichia coli BL21 (DE3) cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50629798(CHEMBL5400763)
Affinity DataIC50: 146nMAssay Description:Inhibition of recombinant human PD-1 (33 to 150 residues)/recombinant human PD-L1 (18 to 134 residues) expressed Escherichia coli BL21 (DE3) cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50629796(CHEMBL5281016)
Affinity DataIC50: 600nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human recombinant extracellular domain PD-L1 in human DU-145 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50237607(CHEBI:45367 | Ansamycin | LM-427 | Mycobutin | Rif...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of biotinylated human PD-I /His-tagged PD-L1 (unknown origin) interaction incubated for 90 mins in dark condition by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM643925(US11866416, Compound SN-I-240j)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50587736(PYRVINIUM | CHEBI:8687 | Pyrvinium | Pyrvinium (ca...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed