Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019538
TargetTrehalose monomycolate exporter MmpL3(Mycolicibacterium smegmatis (strain ATCC 700084 / ...)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50388398(SQ-109 | CHEMBL561057)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to C-terminal 10XHis-tagged Mycobacterium smegmatis mc2 155 MmpL3 expressed in Mycobacterium smegmatis mc2 155 cells by microscale t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTrehalose monomycolate exporter MmpL3(Mycolicibacterium smegmatis (strain ATCC 700084 / ...)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50388398(SQ-109 | CHEMBL561057)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to Mycobacterium smegmatis MmpL3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50620292(CHEMBL1087059)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50620289(CHEMBL5395162)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50620291(CHEMBL5432995)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50011479(CHEMBL3261880)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50388398(SQ-109 | CHEMBL561057)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50620288(CHEMBL5403488)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50011480(CHEMBL3261881)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50620290(CHEMBL5414003)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of UppP in Escherichia coli using FPP as substrate pretreated for 20 mins followed by FPP addition and measured after 60 mins by malachite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed