Compile Data Set for Download or QSAR
Report error Found 172 Enz. Inhib. hit(s) with all data for entry = 50020003
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant HDAC6 using ArgHisLysLys(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM25172(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625506(CHEMBL5407807)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625506(CHEMBL5407807)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant HDAC7 using ArgHisLysLys(Ac) as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 99nMAssay Description:Inhibition of HDAC in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50221965(CHEMBL113303)
Affinity DataIC50: 110nMAssay Description:Inhibition of HDAC1/2 in human K562 nuclear extractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM25162(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625506(CHEMBL5407807)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625506(CHEMBL5407807)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625528(CHEMBL5407992)
Affinity DataIC50: 180nMAssay Description:Inhibition of human full-length recombinant HDAC6 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM25162(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC in human HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 260nMAssay Description:Inhibition of human full-length recombinant HDAC6 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50221784(CHEMBL112211)
Affinity DataIC50: 340nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM207628(US9265734, RGFA8 | US9796664, Compound RGFA8)
Affinity DataIC50: 380nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625506(CHEMBL5407807)
Affinity DataIC50: 700nMAssay Description:Inhibition of HDAC in human HeLa nuclear extractMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM25162(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM25162(1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)thiophen-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625505(CHEMBL5415687)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625528(CHEMBL5407992)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human full-length recombinant HDAC1 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50625505(CHEMBL5415687)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50221938(CHEMBL321253)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of HDAC1/2 in human K562 nuclear extractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50221988(CHEMBL113566)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC1/2 in human K562 nuclear extractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50439672(CHEMBL2417783)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human full-length recombinant HDAC1 incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-Trifluoro-8-oxo-nonanoic acid phenylamide | ...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of HDAC1 in human K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
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