Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50019738
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: 200nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM323495(1-(3-(Cyclohexylmethoxy)Phenyl)-3-(Methylamino)Pro...)
Affinity DataIC50: 290nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622619(CHEMBL5435342)
Affinity DataIC50: 390nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622616(CHEMBL5408189)
Affinity DataIC50: 420nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM323465(3-(3-(Cyclohexylmethoxy)Phenyl)Butan-1-Amine | US1...)
Affinity DataIC50: 820nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622618(CHEMBL5434063)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM323437(3-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-Amine | US...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM323539(2-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Ethanol | U...)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622615(CHEMBL5405037)
Affinity DataIC50: 4.67E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622617(CHEMBL5400176)
Affinity DataIC50: 6.73E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetRetinoid isomerohydrolase(Bovine)
University of California - Irvine

Curated by ChEMBL
LigandPNGBDBM50622614(CHEMBL5404676)
Affinity DataIC50: 8.08E+3nMAssay Description:Inhibition of RPE65 in bovine microsomes assessed as reduction on 11-cis-retinol production incubated for 1 hr by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed