Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50022316
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50058715(CHEMBL64360 | EMD-96785 | N-(diaminomethylene)-2-m...)
Affinity DataIC50: 0.00400nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50485565(CHEMBL465179)
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50234609(Cariporide | HOE-642)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM81818(CHEMBL1909810 | NSC_1794 | CAS_1794 | HMA)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650751(CHEMBL5632207)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of human factor XaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650747(CHEMBL5632554)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant FGFR1 cytoplasmic domain (458 to 756 residues)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650750(CHEMBL5632190)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human factor XaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50270005(cid_1795 | CHEMBL1909809 | CHEMBL517986 | 5'-(N-et...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human NHE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50015448(CHEMBL3265032)
Affinity DataIC50: 11nMAssay Description:Inhibition of SYK (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650749(CHEMBL5632688)
Affinity DataIC50: 26nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650745(CHEMBL5631675)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50593490(CHEMBL5174884)
Affinity DataIC50: 80nMAssay Description:Inhibition of SYK (unknown origin) by Ambit kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650743(CHEMBL5631566)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50643906(CHEMBL2177897)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 6(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50: 210nMAssay Description:Inhibition of ERK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50: 210nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50: 210nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650745(CHEMBL5631675)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650744(CHEMBL5631528)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650743(CHEMBL5631566)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650743(CHEMBL5631566)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50: 466nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50: 583nMAssay Description:Inhibition of BchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650748(CHEMBL5633382)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant FGFR1 (461 to 768 residues) expressed in Escherichia coli BL21 Gold(DE3) cells by spectrophotometer methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650742(CHEMBL5632305)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells incubated for 15 mins by Amplex red and horseradish peroxidase based fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50: 800nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50: 890nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650744(CHEMBL5631528)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650739(CHEMBL5631291)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650741(CHEMBL5633536)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells incubated for 15 mins by Amplex red and horseradish peroxidase based fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of BchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650744(CHEMBL5631528)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650749(CHEMBL5632688)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650745(CHEMBL5631675)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650746(CHEMBL472296)
Affinity DataIC50: 6.47E+3nMAssay Description:Inhibition of human recombinant ALDR1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Gannan Medical University

Curated by ChEMBL
LigandPNGBDBM50650740(CHEMBL5633884)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed