Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50018866
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613361(CHEMBL5279805)
Affinity DataKd:  2.27E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataKd:  1.73E+4nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613356(CHEMBL5273612)
Affinity DataKd:  4.90E+3nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613355(CHEMBL5273501)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613351(CHEMBL5286276)
Affinity DataKd:  2.50E+3nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613364(CHEMBL5267935)
Affinity DataKd:  1.79E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataKd:  1.12E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613355(CHEMBL5273501)
Affinity DataKd:  1.04E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613356(CHEMBL5273612)
Affinity DataKd:  2.30E+3nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613352(CHEMBL5272276)
Affinity DataKd:  2.82E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613363(CHEMBL5268682)
Affinity DataKd:  1.48E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613362(CHEMBL5279446)
Affinity DataKd:  1.81E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613354(CHEMBL5278294)
Affinity DataKd:  4.20E+3nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613360(CHEMBL5270625)
Affinity DataKd:  2.37E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613359(CHEMBL5272803)
Affinity DataKd:  1.95E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613353(CHEMBL5284517)
Affinity DataKd:  2.60E+3nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613358(CHEMBL5267824)
Affinity DataKd:  5.58E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613357(CHEMBL5277756)
Affinity DataKd:  4.51E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataKd:  2.09E+4nMAssay Description:Displacement of FTAD from full-length human DNMT2 expressed in Escherichia coli incubated for 10 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613351(CHEMBL5286276)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613352(CHEMBL5272276)
Affinity DataKd:  3.21E+4nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613353(CHEMBL5284517)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613354(CHEMBL5278294)
Affinity DataKd:  900nMAssay Description:Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613353(CHEMBL5284517)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613356(CHEMBL5273612)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613351(CHEMBL5286276)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613354(CHEMBL5278294)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613350(CHEMBL5285928)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613365(CHEMBL5277079)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human DNMT2 by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613355(CHEMBL5273501)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Human)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50613352(CHEMBL5272276)
Affinity DataIC50: 6.28E+4nMAssay Description:Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed