Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50019879
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624085(CHEMBL5439664)
Affinity DataKd:  376nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTricarboxylate transport protein, mitochondrial(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624084(CHEMBL5421017)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to human SLC25A1 assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTricarboxylate transport protein, mitochondrial(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624083(CHEMBL5416373)
Affinity DataKd:  6.36E+4nMAssay Description:Binding affinity to human SLC25A1 assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant ACLY by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of ACLY (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624080(CHEMBL4757114)
Affinity DataIC50: 24nMAssay Description:Inhibition of SLC13A5 in human HepG2 cells assessed as reduction in citrate uptakeMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624081(CHEMBL5422462)
Affinity DataIC50: 50nMAssay Description:Inhibition of human SLC13A3 in HepG2 cells by measuring citrus uptakeMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624081(CHEMBL5422462)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human SLC13A5 in HEK293T cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624080(CHEMBL4757114)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human SLC13A5 in HEK293T cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624085(CHEMBL5439664)
Affinity DataIC50: 70nMAssay Description:Inhibition of ACLY (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624085(CHEMBL5439664)
Affinity DataIC50: 70nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624082(CHEMBL5405434)
Affinity DataIC50: 160nMAssay Description:Inhibition of human SLC13A3 in HepG2 cells by measuring citrus uptakeMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50394674(CHEMBL2165254)
Affinity DataIC50: 283nMAssay Description:Inhibition of rat liver ACLY incubated for 15 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624087(CHEMBL5393831)
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50394675(PURPURONE)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of ACLY (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 13 member 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of SLC13A5 in human hepatocyte cells assessed as reduction in citrate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624086(CHEMBL5418421)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624088(CHEMBL5438623)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to rat ACLY assessed as inhibition constant measured after 20 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50053000(2-[8-(2,4-Dichloro-phenyl)-2-oxo-octyl]-2-hydroxy-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50052989(2-[8-(2,4-Dichloro-phenyl)-octyl]-2-hydroxy-succin...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50053001(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-su...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50053020(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469150(CHEMBL4287406)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to rat liver ACLY assessed as inhibition constant measured after 15 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469152(CHEMBL4290816)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity to rat liver ACLY assessed as inhibition constant measured after 15 to 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM227589(Radicicol)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity to rat ACLY assessed as inhibition constant measured after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50036210((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity to rat liver ACLY assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM227589(Radicicol)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50018569(CHEMBL63829 | 3,3,14,14-Tetramethyl-hexadecanedioi...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of rat ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50036215((2S,3R)-2-Carboxymethyl-oxirane-2,3-dicarboxylic a...)
Affinity DataKi:  1.80E+4nMAssay Description:Reversible binding affinity to rat ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTricarboxylate transport protein, mitochondrial(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624083(CHEMBL5416373)
Affinity DataKi:  4.80E+4nMAssay Description:Binding affinity to human SLC25A1 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469148(CHEMBL357626)
Affinity DataKi:  2.50E+5nMAssay Description:Reversible binding affinity to rat ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-citrate synthase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM589316(US11555012, Compound I-65 | US20250011272, Example...)
Affinity DataKi:  7.00E+6nMAssay Description:Binding affinity to ACLY (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed