Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50022339
TargetALK tyrosine kinase receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651032(CHEMBL5632806)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 18nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591651(CHEMBL5196257)
Affinity DataIC50: 21nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651035(CHEMBL5634028)
Affinity DataIC50: 24nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651027(CHEMBL5632288)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 74nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651027(CHEMBL5632288)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651039(CHEMBL5218660)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 180nMAssay Description:Inhibition of MIF (unknown origin) tautomerase activity incubated for 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 200nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610592(CHEMBL5272967)
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 290nMAssay Description:Inhibition of full length HDAC1 (unknown origin) by nanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50610592(CHEMBL5272967)
Affinity DataIC50: 330nMAssay Description:Inhibition of LSD-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651029(CHEMBL5633678)
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651040(CHEMBL5632960)
Affinity DataIC50: 460nMAssay Description:Inhibition of full length C-terminal his6-tagged human recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using trypsin and Ac-peptide as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651037(CHEMBL5631734)
Affinity DataIC50: 470nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651038(CHEMBL5632156)
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651031(CHEMBL5631820)
Affinity DataIC50: 525nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651037(CHEMBL5631734)
Affinity DataIC50: 560nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651034(CHEMBL5633685)
Affinity DataIC50: 570nMAssay Description:Inhibition of EphA2 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 600nMAssay Description:Inhibition of C-terminl his-tagged human recombinant HDAC3 (1 to 428 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651036(CHEMBL5633366)
Affinity DataIC50: 620nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651036(CHEMBL5633366)
Affinity DataIC50: 620nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651038(CHEMBL5632156)
Affinity DataIC50: 660nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetEphrin type-A receptor 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651033(CHEMBL5632154)
Affinity DataIC50: 680nMAssay Description:Inhibition of EphA2 (unknown origin) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651040(CHEMBL5632960)
Affinity DataIC50: 710nMAssay Description:Inhibition of IDO1 (unknown origin) incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 729nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 810nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651033(CHEMBL5632154)
Affinity DataIC50: 940nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 960nMAssay Description:Inhibition of full length HDAC1 (unknown origin) by nanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651041(CHEMBL5631367)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human recombinant HDAC2 (1 to 488 residues) expressed in Sf9 cells using fluorogenic Boc-Lys(Ac)-AMC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651037(CHEMBL5631734)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50470579(4sc-202 | Domatinostat)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of LSD-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651038(CHEMBL5632156)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651032(CHEMBL5632806)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651036(CHEMBL5633366)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of HDAC2 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651030(CHEMBL5632251)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651034(CHEMBL5633685)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC or Boc-Lys(Tfa)-AMC as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651029(CHEMBL5633678)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651028(CHEMBL5633576)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651030(CHEMBL5632251)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651028(CHEMBL5633576)
Affinity DataIC50: 9.37E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591651(CHEMBL5196257)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed