Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50020896
TargetPoly [ADP-ribose] polymerase 2(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 1nMAssay Description:Binding affinity for estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 5nMAssay Description:Binding affinity for estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein cereblon/CUL4A/AR(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50094569(Cyproterone 17-O-acetate | cyproterone acetate | C...)
Affinity DataIC50: 7.10nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50094975(US10053433, ARN-509 | ARN-509 | JNJ-56021927 | apa...)
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50556205(Darolutamide | Odm-201 | BAY 1841788 | BAY-1841788...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50076330(Rucaparib camsylate | C0-338 | CO-338 | PF-1367338...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-PDBu from human recombinant Protein kinase C deltaMore data for this Ligand-Target Pair
Ligand InfoCHEMBLPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProtein cereblon/CUL4A/AR(Human)
Zhengzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50131270(2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]prop...)
Affinity DataKi:  55nMAssay Description:In vitro inhibition of [6,7-3H]-17beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed