Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50021422
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640556(CHEMBL5563097)
Affinity DataKi:  0.746nMAssay Description:Binding affinity to human recombinant N-terminal 6His-tagged CD73 (27 to 549 residues) expressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50527650(CHEMBL4438144)
Affinity DataIC50: 12nMAssay Description:Inhibition of Ecto-5'-nucleotidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50165146(CHEMBL3798795)
Affinity DataKi:  18nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50527649(CHEMBL4467828)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50527711(CHEMBL4576728)
Affinity DataIC50: 21nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50527711(CHEMBL4576728)
Affinity DataIC50: 21nMAssay Description:Inhibition of CD73 (unknown origin) expressed as Escherichia coli using AMP as substrate preincubated for 15 mins and measured after 30 mins by malac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM18136(alpha, beta-methyleneadenosine 5 -diphosphate | ci...)
Affinity DataKi:  88nMAssay Description:Binding affinity to human recombinant CD73 (29 to 549 residues) expressed in Escherichia coli assessed as inhibition constant incubated for 1 hr by m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal human recombinant Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640557(CHEMBL5591466)
Affinity DataIC50: 190nMAssay Description:Inhibition of N-terminal human recombinant Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50626469(CHEMBL5428233)
Affinity DataIC50: 250nMAssay Description:Inhibition of N-terminal human recombinant Ecto-5'-nucleotidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human Ecto-5'-nucleotidase expressed in Sf9 cells using AMP as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640561(CHEMBL5574428)
Affinity DataIC50: 470nMAssay Description:Inhibition of N-terminal His-tagged human recombinant CD73 (27 to 527 residues) expressed in CHO cells incubated for 1 hr by malachite green based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640559(CHEMBL5572739)
Affinity DataIC50: 560nMAssay Description:Inhibition of N-terminal His-tagged human recombinant CD73 (27 to 527 residues) expressed in CHO cells incubated for 1 hr by malachite green based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640560(CHEMBL5573566)
Affinity DataIC50: 740nMAssay Description:Inhibition of N-terminal His-tagged human recombinant CD73 (27 to 527 residues) expressed in CHO cells incubated for 1 hr by malachite green based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50640558(CHEMBL3417457)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant CD73 (27 to 527 residues) expressed in CHO cells incubated for 1 hr by malachite green based sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5'-nucleotidase(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM222261((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...)
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of human Ecto-5'-nucleotidase expressed in Sf9 cells using AMP as substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed