Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50021008
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM724380(US20250066350, Example RP3500)
Affinity DataIC50: 0.330nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM268079(2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730138(US12264155, Compound 24)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM724380(US20250066350, Example RP3500)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730169(US12264155, Compound 56)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635967(CHEMBL5560075)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM268079(2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730175(US12264155, Compound 62)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635969(CHEMBL5562229)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635968(CHEMBL5542914)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730170(US12264155, Compound 57)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635964(CHEMBL5560123)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730157(US12264155, Compound 43)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635963(CHEMBL5555424)
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730117(US12264155, Compound 3)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730118(US12264155, Compound 4)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730117(US12264155, Compound 3)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635966(CHEMBL5560048)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50585017(CERALASERTIB | Ceralasertib | Atr kinase inhibitor...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635965(CHEMBL5558939)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730116(US12264155, Compound 2)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730149(US12264155, Compound 35)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50585017(CERALASERTIB | Ceralasertib | Atr kinase inhibitor...)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635955(CHEMBL5568570)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635962(CHEMBL5561193)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM730149(US12264155, Compound 35)
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 74nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635955(CHEMBL5568570)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635957(CHEMBL5556905)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50585017(CERALASERTIB | Ceralasertib | Atr kinase inhibitor...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM268079(2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...)
Affinity DataIC50: 330nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635959(CHEMBL5532160)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635960(CHEMBL5564966)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635958(CHEMBL5557127)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50635956(CHEMBL5518146)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 3.60E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50585017(CERALASERTIB | Ceralasertib | Atr kinase inhibitor...)
Affinity DataIC50: 3.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM350086(US10208027, Compound II-2 | 3-[3-[4-[dideuterio-(t...)
Affinity DataIC50: 4.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Repare Therapeutics, Inc.

Curated by ChEMBL
LigandPNGBDBM50427326(CHEMBL2325697)
Affinity DataIC50: 7.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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