Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50020791
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant His-tagged SAR-CoV-2 Main protease expressed in Escherichia coli BL21/DE3 using Edans-labeled substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant His-tagged SAR-CoV-2 Main protease expressed in Escherichia coli BL21/DE3 using MCA-labeled substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant SARS-CoV-2 Native Main protease expressed in Escherichia coli using MCA-labeled substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM448319(GC376 | GC-376 | US20250188102, Compound GC-376)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant SARS-CoV-2 Native Main protease expressed in Escherichia coli using using Edans-labeled substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50633627(CHEMBL5403045)
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-2 Main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 350nMAssay Description:Inhibition of SARS-CoV-2 Main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200395((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of SARS-CoV-2 Main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50633626(CHEMBL5430305)
Affinity DataIC50: 3.27E+3nMAssay Description:Non-covalent inhibition of recombinant SARS-CoV-2 Native Main protease expressed in Escherichia coli using MCA-labeled substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50633626(CHEMBL5430305)
Affinity DataIC50: 3.68E+3nMAssay Description:Non-covalent inhibition of recombinant SARS-CoV-2 Native Main protease expressed in Escherichia coli using using Edans-labeled substrate by FRET-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50633626(CHEMBL5430305)
Affinity DataIC50: 7.40E+3nMAssay Description:Non-covalent inhibition of recombinant His-tagged SAR-CoV-2 Main protease expressed in Escherichia coli BL21/DE3 using MCA-labeled substrate by FRET-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of SARS-CoV-2 Main protease by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50633626(CHEMBL5430305)
Affinity DataIC50: 4.48E+4nMAssay Description:Non-covalent inhibition of recombinant His-tagged SAR-CoV-2 Main protease expressed in Escherichia coli BL21/DE3 using Edans-labeled substrate by FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed