Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50021816
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of human PARP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645125(CHEMBL5574820)
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645124(CHEMBL5566523)
Affinity DataIC50: 1nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645133(CHEMBL5572999)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PARP2 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626789(CHEMBL5441085)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645127(CHEMBL5570455)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645121(CHEMBL5566919)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50611327(CHEMBL5276959)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50611322(CHEMBL5274535)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645133(CHEMBL5572999)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PARP1 (unknown origin) using biotinylated NAD+ as substrate by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626789(CHEMBL5441085)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645130(CHEMBL5566839)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human recombinant PARP1 expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645131(CHEMBL5572956)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PARP1 expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 17nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609913(CHEMBL5274451)
Affinity DataIC50: 20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626785(CHEMBL5396891)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant PARP-1 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 28nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645122(CHEMBL5571005)
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609913(CHEMBL5274451)
Affinity DataIC50: 30nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645122(CHEMBL5571005)
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645132(CHEMBL5570496)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant PARP-1 by ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645128(CHEMBL5565569)
Affinity DataIC50: 57nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645129(CHEMBL5565927)
Affinity DataIC50: 70nMAssay Description:Inhibition of PARP3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645120(CHEMBL5564571)
Affinity DataIC50: 140nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645119(CHEMBL5575086)
Affinity DataIC50: 170nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645123(CHEMBL5571183)
Affinity DataIC50: 720nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645123(CHEMBL5571183)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645126(CHEMBL5590396)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645126(CHEMBL5590396)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed