Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50021561
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717900(US20250042857, Example A-6)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717931(US20250042857, Example B-38)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717922(US20250042857, Example B-23)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717899(US20250042857, Example A-5)
Affinity DataIC50: 6nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717897(US20250042857, Example A-3)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717932(US20250042857, Example B-41)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717920(US20250042857, Example B-21)
Affinity DataIC50: 7nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717923(US20250042857, Example B-24)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641969(CHEMBL5592526)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641968(CHEMBL5583880)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717918(US20250042857, Example B-4)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641964(CHEMBL5584077)
Affinity DataIC50: 10nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717906(US20250042857, Example A-40)
Affinity DataIC50: 11nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717895(US20250042857, Example A-1)
Affinity DataIC50: 11nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717930(US20250042857, Example B-37)
Affinity DataIC50: 12nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641971(CHEMBL5575769)
Affinity DataIC50: 13nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717903(US20250042857, Example A-17)
Affinity DataIC50: 13nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641965(CHEMBL5570758)
Affinity DataIC50: 13nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641967(CHEMBL5570028)
Affinity DataIC50: 14nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641970(CHEMBL5571673)
Affinity DataIC50: 15nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641963(CHEMBL5595806)
Affinity DataIC50: 15nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50614629(BAY-293)
Affinity DataIC50: 21nMAssay Description:Inhibition of SOS1/KRAS G12D mutant (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717996(US20250042857, Example B-110)
Affinity DataIC50: 22nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50641966(CHEMBL5594101)
Affinity DataIC50: 23nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed