Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50021841
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645400(CHEMBL5564820)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565160(US11414404, Ex. # 37 | N-(2-chloro-3-((3-ethyl-5- ...)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645399(CHEMBL5573455)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645400(CHEMBL5564820)
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645399(CHEMBL5573455)
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565154(US11414404, Ex. # 31 | N-(2-chloro-3-((3- cyclopro...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496939(CHEMBL3236198)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565132(US11414404, Ex. # 9 | BDBM565147 | US11634409, Exa...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565146(US11414404, Ex. # 23)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565161(US11414404, Ex. # 38 | N-(2-chloro-3-((3- (cyclopr...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565159(US11414404, Ex. # 36 | N-(2-chloro-4-fluoro-3-((3-...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565160(US11414404, Ex. # 37 | N-(2-chloro-3-((3-ethyl-5- ...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496939(CHEMBL3236198)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496937(CHEMBL3233047)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645397(CHEMBL5572717)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565132(US11414404, Ex. # 9 | BDBM565147 | US11634409, Exa...)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645397(CHEMBL5572717)
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565173(US11414404, Ex. # 50 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565174(US11414404, Ex. # 51 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565146(US11414404, Ex. # 23)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496942(CHEMBL3236467)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496936(CHEMBL3236462)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565154(US11414404, Ex. # 31 | N-(2-chloro-3-((3- cyclopro...)
Affinity DataIC50: 62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496952(CHEMBL3236466)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496951(CHEMBL3236461)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496952(CHEMBL3236466)
Affinity DataIC50: 74nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565184(US11414404, Ex. # 61 | N-(2-chloro-3-((3,5-dimethy...)
Affinity DataIC50: 77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496951(CHEMBL3236461)
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565173(US11414404, Ex. # 50 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565184(US11414404, Ex. # 61 | N-(2-chloro-3-((3,5-dimethy...)
Affinity DataIC50: 113nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565174(US11414404, Ex. # 51 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 122nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645402(CHEMBL5563407)
Affinity DataIC50: 141nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496936(CHEMBL3236462)
Affinity DataIC50: 142nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645401(CHEMBL5570852)
Affinity DataIC50: 157nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565175(US11414404, Ex. # 52 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 169nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496942(CHEMBL3236467)
Affinity DataIC50: 177nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496937(CHEMBL3233047)
Affinity DataIC50: 178nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565175(US11414404, Ex. # 52 | N-(2-chloro-3-((3,5- dimeth...)
Affinity DataIC50: 182nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565159(US11414404, Ex. # 36 | N-(2-chloro-4-fluoro-3-((3-...)
Affinity DataIC50: 187nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496934(CHEMBL3236468)
Affinity DataIC50: 197nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50496934(CHEMBL3236468)
Affinity DataIC50: 197nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645402(CHEMBL5563407)
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645398(CHEMBL5572505)
Affinity DataIC50: 256nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645401(CHEMBL5570852)
Affinity DataIC50: 267nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM565161(US11414404, Ex. # 38 | N-(2-chloro-3-((3- (cyclopr...)
Affinity DataIC50: 285nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Enliven Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645398(CHEMBL5572505)
Affinity DataIC50: 291nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed