Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022145
TargetPhosphoserine aminotransferase(Homo sapiens)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human PSAT extracted from Escherichia coli BL21(DE3) cells preincubated with compound followed by L-OPS addition in presence of PLPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells assessed as dissociation con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648628(CHEMBL5611941)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648629(CHEMBL5613082)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant hexa-His tagged human SR extracted from Escherichia coli BL21 CodonPlusR (DE3)-RIL cells preincubated with compound followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648631(CHEMBL5614231)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human SR incubated for 30 mins by chemiluminescence based luminometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Mouse)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50357231(L-CYCLOSERINE)
Affinity DataIC50: 2.27E+6nMAssay Description:Inhibition of mouse SR using L-Serine as substrate incubated for 2 hrs in presence of PLP by spectrophotometer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSerine racemase(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50648630(CHEMBL5614081)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human SR extracted from Escherichia coli assessed as beta-eliminase activity using L-Ser as substrate by spectrophotometer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed