Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50023731
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667409BDBM50667409(CHEMBL6189670)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667414BDBM50667414(CHEMBL6190298)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 293051BDBM293051(US20260015358, Example 7)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667410BDBM50667410(CHEMBL6188722)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 770821BDBM770821(2-(6-(4-(3H-imidazo[4,5-c]pyridine-4-carbonyl)pipe...)
Affinity DataIC50: 29nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667415BDBM50667415(CHEMBL6192156)
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 770824BDBM770824(2-(6-(4-(1H-pyrrolo[2,3-c]pyridine-7-carbonyl)pipe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667416BDBM50667416(CHEMBL6191248)
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667411BDBM50667411(CHEMBL6189259)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667412BDBM50667412(CHEMBL6188815)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667413BDBM50667413(CHEMBL6188838)
Affinity DataIC50: 71nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 646442BDBM646442(US11878973, Example 123)
Affinity DataIC50: 88nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667427BDBM50667427(CHEMBL6189223)
Affinity DataIC50: 111nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667426BDBM50667426(CHEMBL6189708)
Affinity DataIC50: 125nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667423BDBM50667423(CHEMBL6193240)
Affinity DataIC50: 128nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 332553BDBM332553(US20260015358, Example 266)
Affinity DataIC50: 129nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 293127BDBM293127(US20260015358, Example 86)
Affinity DataIC50: 166nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667418BDBM50667418(CHEMBL6190409)
Affinity DataIC50: 186nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667417BDBM50667417(CHEMBL6191711)
Affinity DataIC50: 194nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667422BDBM50667422(CHEMBL6188538)
Affinity DataIC50: 205nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667431BDBM50667431(CHEMBL6191085)
Affinity DataIC50: 212nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 293132BDBM293132(US20260015358, Example 91)
Affinity DataIC50: 223nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667430BDBM50667430(CHEMBL6192212)
Affinity DataIC50: 362nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667421BDBM50667421(CHEMBL6189507)
Affinity DataIC50: 379nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667436BDBM50667436(CHEMBL6193579)
Affinity DataIC50: 432nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667435BDBM50667435(CHEMBL6192978)
Affinity DataIC50: 499nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667437BDBM50667437(CHEMBL6190869)
Affinity DataIC50: 568nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667424BDBM50667424(CHEMBL6193213)
Affinity DataIC50: 597nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667432BDBM50667432(CHEMBL6188888)
Affinity DataIC50: 647nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667434BDBM50667434(CHEMBL6189331)
Affinity DataIC50: 651nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667429BDBM50667429(CHEMBL6191066)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667428BDBM50667428(CHEMBL6188457)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667433BDBM50667433(CHEMBL6188836)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667420BDBM50667420(CHEMBL6192812)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667425BDBM50667425(CHEMBL6193125)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667419BDBM50667419(CHEMBL6189711)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of N-terminal FLAG-tagged human full length WRN expressed in baculovirus-infected Sf9 cells assessed as inhibition of ATPase activity usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed