Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50028983
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: 16nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: 22nMAssay Description:Concentration required to inhibit monkey plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280493({(S)-1-[(S)-1-((S)-1-Cyclohexylmethyl-3,3,3-triflu...)
Affinity DataIC50: 250nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280490((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: 3.00E+3nMAssay Description:Concentration required to inhibit dog plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280491((S)-6-(4-Methoxy-phenyl)-5-(3-methyl-butyrylamino)...)
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280494(N-[(S)-1-[(R)-1-((S)-4-Amino-1-cyclohexylmethyl-3,...)
Affinity DataIC50: 2.70E+4nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280492((S)-2-{[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Concentration required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit rat plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetChymotrypsinogen A(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  2.50E+3nMAssay Description:Concentration required to inhibit the enzyme chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+3nMAssay Description:Concentration required to inhibit the enzyme cathepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+4nMAssay Description:Concentration required to inhibit the enzyme pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article