Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50029086
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 9nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281324(((S)-1-{N'-[(2S,3S)-3-((S)-2-Benzyloxycarbonylamin...)
Affinity DataIC50: 10nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281333({(S)-1-[N'-[(2S,3S)-3-((S)-2-Benzyloxycarbonylamin...)
Affinity DataIC50: 22nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281332({(S)-1-[N'-[(2S,3S)-3-((S)-2-Benzyloxycarbonylamin...)
Affinity DataIC50: 24nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281328((S)-2-Acetylamino-N-{(1S,2S)-3-[N'-((S)-2-acetylam...)
Affinity DataIC50: 28nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281330((S)-2-Acetylamino-N-{(1S,2S)-3-[N'-((R)-2-acetylam...)
Affinity DataIC50: 30nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281335(((R)-1-{N'-Benzyl-N'-[(2S,3S)-3-((S)-2-benzyloxyca...)
Affinity DataIC50: 33nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281327((S)-2-Acetylamino-N-{(1S,2S)-3-[N'-((S)-2-acetylam...)
Affinity DataIC50: 45nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281337((S)-2-Acetylamino-N-{(1S,2S)-3-[N'-((S)-2-acetylam...)
Affinity DataIC50: 50nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281329(quinoline-2-carboxylic acid {(S)-1-[(1S,2S)-1-benz...)
Affinity DataIC50: 65nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281323(((S)-1-{N'-[(2S,3S)-3-((S)-2-Benzyloxycarbonylamin...)
Affinity DataIC50: 95nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281334((S)-N-{(1S,2S)-1-Benzyl-3-[N-benzyl-N'-((R)-3-meth...)
Affinity DataIC50: 360nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281338((S)-N-((1S,2S)-1-Benzyl-3-{N-benzyl-N'-[(R)-3-meth...)
Affinity DataIC50: 500nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGastricsin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 1.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human gastricsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCathepsin E(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 2.00E+3nMAssay Description:The compound was tested for its inhibitory activity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281336(morpholine-4-carboxylic acid {(S)-1-[(1S,2S)-1-ben...)
Affinity DataIC50: 2.00E+3nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 7.50E+3nMAssay Description:The compound was tested for its inhibitory activity against human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281331(((R)-1-{N'-Benzyl-N'-[(2S,3S)-3-((S)-2-tert-butoxy...)
Affinity DataIC50: 5.20E+4nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM201((2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-ac...)
Affinity DataIC50: 5.80E+4nMAssay Description:The compound was tested for its inhibitory activity against human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281326(2-Amino-N-{(S)-3-[N'-((R)-2-amino-3-methyl-butyryl...)
Affinity DataIC50: 1.00E+5nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281325(((S)-1-{N'-Benzyl-N'-[(2S,3S)-3-((R)-2-benzyloxyca...)
Affinity DataIC50: 1.00E+5nMpH: 6.0Assay Description:In vitro inhibition of HIV-1 protease at pH 6 using 164 uM peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article