Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50029508
LigandPNGBDBM50048248(methyl 3-acetyl-4-(3-cyclopentyloxy-4-methoxypheny...)
Affinity DataIC50: 320nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50048248(methyl 3-acetyl-4-(3-cyclopentyloxy-4-methoxypheny...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285059(1-(tert-butyl) 3-methyl 4-(3-cyclopentyloxy-4-meth...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285045(1-isopropyl 3-methyl 4-(3-cyclopentyloxy-4-methoxy...)
Affinity DataKi:  40nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285038(1-benzyl 3-methyl 4-(3-cyclopentyloxy-4-methoxyphe...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285042(tert-butyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285050(methyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-nitr...)
Affinity DataKi:  60nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285041(methyl 3-cyano-4-(3-cyclopentyloxy-4-methoxyphenyl...)
Affinity DataKi:  80nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285057(tert-butyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-...)
Affinity DataKi:  80nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285049((3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrr...)
Affinity DataKi:  150nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50048243(dimethyl4-(3-cyclopentyloxy-4-methoxyphenyl)-(3S,4...)
Affinity DataKi:  160nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285061(tert-butyl 3-carbamoyl-4-(3-cyclopentyloxy-4-metho...)
Affinity DataKi:  190nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataKi:  220nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50285054(1-(tert-butyl) 3-methyl 4-[4-methoxy-3-(3-phenoxyp...)
Affinity DataKi:  240nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285063((3S,4R)-3-tert-Butoxycarbonylamino-4-(3-cyclopenty...)
Affinity DataKi:  290nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285062(methyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-prop...)
Affinity DataKi:  350nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285056(methyl 1-amino(thioxo)methyl-4-(3-cyclopentyloxy-4...)
Affinity DataKi:  380nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50048245((3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrr...)
Affinity DataKi:  550nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285043(methyl 4-(3-cyclopentyloxy-4-methoxyphenyl)-1-form...)
Affinity DataKi:  810nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285048(methyl 4-(3-cyclopentyloxy-4-methoxyphenyl)-1-prop...)
Affinity DataKi:  1.13E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285053(1-(tert-butyl) 3-methyl 4-(3,4-dimethoxyphenyl)-(3...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285039(benzyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-meth...)
Affinity DataKi:  1.47E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285055(methyl 1-carbamoyl-4-(3-cyclopentyloxy-4-methoxyph...)
Affinity DataKi:  1.48E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285040((3S,4R)-3-tert-Butoxycarbonylamino-4-(3-cyclopenty...)
Affinity DataKi:  1.57E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285046((3S,4R)-3-Carbamoyl-4-(3-cyclopentyloxy-4-methoxy-...)
Affinity DataKi:  1.57E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285047((3S,4R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrr...)
Affinity DataKi:  1.88E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285052(3-isopropyl 1-methyl 4-(3-cyclopentyloxy-4-methoxy...)
Affinity DataKi:  2.29E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285051(benzyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-phen...)
Affinity DataKi:  4.42E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285060(3-(tert-butyl) 1-methyl 4-(3-cyclopentyloxy-4-meth...)
Affinity DataKi:  4.63E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285044(methyl 3-benzoyl-4-(3-cyclopentyloxy-4-methoxyphen...)
Affinity DataKi:  6.03E+3nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50285058((3S,4R)-3-tert-Butoxycarbonylamino-4-(3-cyclopenty...)
Affinity DataKi:  1.44E+4nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article