Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50029625
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051456(N-(2,6-Diisopropyl-phenyl)-2-(2-dodecyl-2H-tetrazo...)
Affinity DataIC50: 10nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051460(2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...)
Affinity DataIC50: 14nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50450396(CHEMBL102912)
Affinity DataIC50: 22nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051460(2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...)
Affinity DataIC50: 24nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051460(2-(2-Dodecyl-2H-tetrazol-5-yl)-2-phenyl-N-(2,4,6-t...)
Affinity DataIC50: 24nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50450398(CHEMBL100448)
Affinity DataIC50: 52nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50450397(CHEMBL103748)
Affinity DataIC50: 79nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details

TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005944(2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...)
Affinity DataIC50: 110nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details
PDB3D3D Structure (crystal)
TargetSterol O-acyltransferase 1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50450395(CHEMBL318600)
Affinity DataIC50: 160nMAssay Description:Concentration required for the in vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in liver microsomes isolated from cholestero...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details