Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50029785
LigandPNGBDBM50287851((S)-2-(3-Fluoro-phenoxymethyl)-azetidine | CHEMBL3...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287814((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Affinity DataKi:  5nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287829((R)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...)
Affinity DataKi:  13nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287812((S)-2-(3-Fluoro-phenoxymethyl)-pyrrolidine | CHEMB...)
Affinity DataKi:  14nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287821((S)-2-(3-Fluoro-phenoxymethyl)-1-methyl-azetidine ...)
Affinity DataKi:  14nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287838((S)-2-(3,4-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Affinity DataKi:  17nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287834(3-((S)-1-Pyrrolidin-2-ylmethoxy)-benzonitrile | CH...)
Affinity DataKi:  18nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287816((S)-2-(3,5-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Affinity DataKi:  18nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287848((S)-2-(3,4-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Affinity DataKi:  18nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287849((S)-2-(3,5-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Affinity DataKi:  19nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287852((S)-2-(3-Chloro-phenoxymethyl)-1-methyl-pyrrolidin...)
Affinity DataKi:  37nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287824((S)-1-Methyl-2-phenoxymethyl-pyrrolidine | CHEMBL7...)
Affinity DataKi:  42nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287820(3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-benzonitri...)
Affinity DataKi:  51nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287843((S)-2-Phenoxymethyl-azetidine | CHEMBL72031)
Affinity DataKi:  52nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287825((S)-2-(2,3-Difluoro-phenoxymethyl)-1-methyl-pyrrol...)
Affinity DataKi:  69nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287846((S)-2-(2,3-Difluoro-phenoxymethyl)-pyrrolidine | C...)
Affinity DataKi:  77nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287854((R)-2-(3-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Affinity DataKi:  78nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287842((S)-1-Methyl-2-phenoxymethyl-azetidine | CHEMBL754...)
Affinity DataKi:  101nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287830((R)-2-Phenoxymethyl-pyrrolidine | CHEMBL73784)
Affinity DataKi:  107nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287844((S)-2-(3,4-Dichloro-phenoxymethyl)-1-methyl-pyrrol...)
Affinity DataKi:  112nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287855(3-((S)-1-Pyrrolidin-2-ylmethoxy)-benzamide | CHEMB...)
Affinity DataKi:  136nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287835((S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-1-methyl-py...)
Affinity DataKi:  169nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287850((S)-2-(3-Methoxy-phenoxymethyl)-1-methyl-pyrrolidi...)
Affinity DataKi:  175nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287813((S)-2-Phenoxymethyl-pyrrolidine | CHEMBL418900)
Affinity DataKi:  195nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287826((R)-1-Methyl-2-phenoxymethyl-pyrrolidine | CHEMBL7...)
Affinity DataKi:  204nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287828((S)-2-(2-Fluoro-phenoxymethyl)-1-methyl-pyrrolidin...)
Affinity DataKi:  304nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287832(6-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-3,3-dioxo-...)
Affinity DataKi:  339nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287819((S)-2-(3-Methoxy-phenoxymethyl)-pyrrolidine | CHEM...)
Affinity DataKi:  468nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287840((S)-2-(3-Trifluoromethyl-phenoxymethyl)-pyrrolidin...)
Affinity DataKi:  523nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287837((S)-1-Methyl-2-(3-trifluoromethyl-phenoxymethyl)-p...)
Affinity DataKi:  557nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287827((S)-1-Methyl-2-(naphthalen-1-yloxymethyl)-pyrrolid...)
Affinity DataKi:  592nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287845((S)-2-(4-Chloro-phenoxymethyl)-1-methyl-pyrrolidin...)
Affinity DataKi:  603nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287818(((S)-2-Phenoxymethyl-pyrrolidin-1-yl)-acetonitrile...)
Affinity DataKi:  1.06E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287853((S)-2-(3-Fluoro-phenylsulfanylmethyl)-1-methyl-pyr...)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287857((S)-2-(7-Chloro-indan-4-yloxymethyl)-1-methyl-pyrr...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287817((S)-1-Methyl-2-(2-trifluoromethyl-phenoxymethyl)-p...)
Affinity DataKi:  2.43E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287831((S)-2-(Naphthalen-1-yloxymethyl)-pyrrolidine | CHE...)
Affinity DataKi:  2.89E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287847((S)-2-Pentafluorophenyloxymethyl-pyrrolidine | CHE...)
Affinity DataKi:  3.07E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287815(1-[2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-phenyl]...)
Affinity DataKi:  3.33E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287833(7-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-quinoline ...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287822(Phenyl-(S)-1-pyrrolidin-2-ylmethyl-amine | CHEMBL3...)
Affinity DataKi:  5.09E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287841((S)-1-Ethyl-2-phenoxymethyl-pyrrolidine | CHEMBL30...)
Affinity DataKi:  5.17E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287836((S)-2-(3-Fluoro-phenylsulfanylmethyl)-pyrrolidine ...)
Affinity DataKi:  5.41E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287823((S)-2-(Naphthalen-2-yloxymethyl)-pyrrolidine | CHE...)
Affinity DataKi:  6.89E+3nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287839((S)-2-(2-Trifluoromethyl-phenoxymethyl)-pyrrolidin...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50287856((S)-1-Methyl-2-pentafluorophenyloxymethyl-pyrrolid...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article