Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50029792
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287928(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50: 2.20nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataIC50: 5.60nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50: 13nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287927(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50: 13nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataIC50: 1.71E+4nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  0.0700nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287928(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287927(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287928(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.230nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  0.400nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.600nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287927(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  0.800nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  0.900nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  3.10nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287928(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  5nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287927(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  5.10nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  9.60nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50248793(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-e...)
Affinity DataKi:  13nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  22nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287927(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  31nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287928(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  48nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50247803(Beta-Funeltrexamine | beta-funaltrexamine | methyl...)
Affinity DataKi:  67nMAssay Description:Compound was evaluated for binding affinity against [3H]- bremazocine labeled kappa2 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50287929(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14...)
Affinity DataKi:  171nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article