Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50029882
TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288994(N'-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tet...)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288991(N'-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tet...)
Affinity DataIC50: 3.50E+3nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288989(N'-((S)-4,11-Diethyl-4-hydroxy-3,13-dioxo-3,4,12,1...)
Affinity DataIC50: 3.60E+3nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50008936(cid_72402 | 9-aminocamptothecan | CHEMBL274070 | 1...)
Affinity DataIC50: 4.20E+3nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288988(N-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetr...)
Affinity DataIC50: 6.60E+3nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288993(N'-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tet...)
Affinity DataIC50: 1.92E+4nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288992(N-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetr...)
Affinity DataIC50: 2.04E+4nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288995(N'-((S)-4-Ethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tet...)
Affinity DataIC50: 4.20E+4nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetDNA topoisomerase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288990((S)-4-Ethyl-4-hydroxy-10-{[1-morpholin-4-yl-meth-(...)
Affinity DataIC50: 6.90E+4nMAssay Description:Compound was tested in vitro for inhibition of topoisomerase I.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article