Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50029916
TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  6nMAssay Description:In vitro binding affinity of compound against histamine H1 neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  7nMAssay Description:In vitro binding affinity of compound against histamine H1 neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  9nMAssay Description:In vitro binding affinity of compound against neuronal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity of compound against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity of compound against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity of compound against neuronal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity of compound against histamine H1 neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  22nMAssay Description:In vitro binding affinity of compound against neuronal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  23nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  66nMAssay Description:In vitro binding affinity of compound against dopamine neuronal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  68nMAssay Description:In vitro binding affinity of compound against muscarinic neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  80nMAssay Description:In vitro binding affinity of compound against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  87nMAssay Description:In vitro binding affinity of compound against histamine H1 neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  112nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  119nMAssay Description:In vitro binding affinity of compound against dopamine neuronal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  119nMAssay Description:In vitro binding affinity of compound against neuronal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  203nMAssay Description:In vitro binding affinity of compound against dopamine neuronal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  263nMAssay Description:In vitro binding affinity of compound against neuronal alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  266nMAssay Description:In vitro binding affinity of compound against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  333nMAssay Description:In vitro binding affinity of compound against muscarinic neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(1A) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  395nMAssay Description:In vitro binding affinity of compound against dopamine neuronal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  501nMAssay Description:In vitro binding affinity of compound against muscarinic neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  662nMAssay Description:In vitro binding affinity of compound against muscarinic neuronal receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi:  783nMAssay Description:In vitro binding affinity of compound against neuronal alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro binding affinity of compound against neuronal alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289291([10-(4-Methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50240701(CHEMBL1125 | 2-Methyl-10-piperazin-1-yl-4H-3-thia-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity of compound against neuronal Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article