Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50029919
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 2nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289328(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-trifluorom...)
Affinity DataIC50: 3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289327(5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...)
Affinity DataIC50: 3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 6nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289323(5-(4-Methanesulfonyl-phenyl)-6-phenyl-thiazolo[3,2...)
Affinity DataIC50: 10nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289324(2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-...)
Affinity DataIC50: 11nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289331(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 13nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289332(2-Ethyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thia...)
Affinity DataIC50: 15nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 18nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289319(5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-thi...)
Affinity DataIC50: 20nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289317(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: 22nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 26nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289325(6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...)
Affinity DataIC50: 32nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289316(6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: 36nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289326(6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 48nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 59nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 60nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289330(6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 80nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289315(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 150nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289322(5-(4-Methanesulfonyl-phenyl)-6-phenyl-thiazolo[2,3...)
Affinity DataIC50: 230nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289320(5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-...)
Affinity DataIC50: 260nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289318(6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[2,3...)
Affinity DataIC50: 450nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 460nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289324(2-Isopropyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-...)
Affinity DataIC50: 600nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289327(5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...)
Affinity DataIC50: 610nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289328(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-trifluorom...)
Affinity DataIC50: 1.10E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289322(5-(4-Methanesulfonyl-phenyl)-6-phenyl-thiazolo[2,3...)
Affinity DataIC50: 2.10E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289323(5-(4-Methanesulfonyl-phenyl)-6-phenyl-thiazolo[3,2...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289332(2-Ethyl-5-(4-methanesulfonyl-phenyl)-6-phenyl-thia...)
Affinity DataIC50: 2.40E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 4.10E+3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289317(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289331(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 8.50E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289329(6-(4-Methanesulfonyl-phenyl)-5-phenyl-2-trifluorom...)
Affinity DataIC50: 9.00E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289321(5-(4-Methanesulfonyl-phenyl)-6-phenyl-2-vinyl-thia...)
Affinity DataIC50: 9.60E+3nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289319(5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289315(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289316(6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: 1.50E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289326(6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289326(6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289325(6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289323(5-(4-Methanesulfonyl-phenyl)-6-phenyl-thiazolo[3,2...)
Affinity DataIC50: 4.30E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289315(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289329(6-(4-Methanesulfonyl-phenyl)-5-phenyl-2-trifluorom...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289330(6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289317(6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289320(5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289319(5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-thi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289325(6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289318(6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[2,3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article