Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50029928
TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289397(3-[(1-{3-Methyl-2-[(naphthalene-2-carbonyl)-amino]...)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289410(Peptidic phenyl ketoether analogue | CHEMBL26544)
Affinity DataKi:  0.150nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289398(Peptidic phenyl ketoether analogue | CHEMBL553107)
Affinity DataKi:  0.200nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289405(Peptidic phenyl ketoether analogue | CHEMBL2371932)
Affinity DataKi:  1.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50084633(3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo-2,3...)
Affinity DataKi:  1.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289402((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289412((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.5nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50091577(3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo-2H-...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289393((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  1.80nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289407((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289388((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  2.20nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289408((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  5.30nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289400((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  7nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289403((S)-3-(3-Methoxy-2-{3-[(naphthalene-2-carbonyl)-am...)
Affinity DataKi:  7.10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289387((S)-3-(2-{6-Benzyl-3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  10nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289409((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  14nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289395((S)-3-(2-{6-Butyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  16nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289411((S)-3-(3-Methyl-2-{3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  21nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289404((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  25nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289390((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  39nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289399((S)-3-(2-{6-Ethyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289414((S)-3-(2-{6-Hexyl-3-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  40nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289415((S)-3-(2-{3-[(Naphthalene-2-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  45nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289394((S)-3-(2-{2-Butyl-5-[(naphthalene-1-carbonyl)-amin...)
Affinity DataKi:  46nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289401((S)-3-(2-{5-[(Naphthalene-1-carbonyl)-amino]-6-oxo...)
Affinity DataKi:  66nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289386((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  68nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289396((S)-3-(2-{6-Methyl-3-[(naphthalene-1-carbonyl)-ami...)
Affinity DataKi:  95nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289413((S)-3-(2-{6-Methyl-3-[(naphthalene-2-carbonyl)-ami...)
Affinity DataKi:  160nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289391((S)-3-[2-(3-Benzoylamino-6-methyl-2-oxo-2H-pyridin...)
Affinity DataKi:  530nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289406((S)-3-[2-(3-Benzyloxycarbonylamino-6-methyl-2-oxo-...)
Affinity DataKi:  590nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289389((S)-3-(2-{6-Methyl-3-[(naphthalene-2-carbonyl)-ami...)
Affinity DataKi:  2.20E+3nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCaspase-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289392((S)-3-(2-{3-[(Naphthalene-1-carbonyl)-amino]-2-oxo...)
Affinity DataKi:  7.20E+3nMAssay Description:Reversible inhibition of recombinant human IL-1 beta converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article