Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50029951
TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099216((2S,3S)-1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-...)
Affinity DataIC50: 226nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099216((2S,3S)-1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-...)
Affinity DataIC50: 226nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289630((2S,3S)-3-Benzyl-1-[2-(3-carboxy-phenyl)-acetyl]-4...)
Affinity DataIC50: 1.34E+3nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099218((2S,3S)-3-Benzyl-1-[2-(3-benzyloxycarbonyl-phenyl)...)
Affinity DataIC50: 1.43E+3nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099221(1-[2-(3-Benzyloxycarbonyl-phenyl)-acetyl]-3-(4-hyd...)
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099213(3-Benzyl-1-{2-[3-(4-carboxy-benzyloxycarbonyl)-phe...)
Affinity DataIC50: 5.84E+3nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099205((2S,3S)-3-Benzyl-1-[2-(3-benzyloxycarbonyl-phenyl)...)
Affinity DataIC50: 8.98E+3nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlutamate carboxypeptidase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50099208(3-Benzyl-1-[2-(3-carboxy-phenyl)-acetyl]-4-oxo-aze...)
Affinity DataIC50: 3.00E+4nMAssay Description:Concentration required for inhibition of 50% of the cleavage of para-nitroanilide from MeO-Suc-Arg-Pro-Tyr-pNA.HCl by Prostate specific antigen PSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article