Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50030083
TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073850([(S)-1-(1-Benzyl-2-oxo-ethylcarbamoyl)-2-methyl-pr...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287391((R)-4-Methyl-2-[2-oxo-2-(9H-xanthen-9-yl)-ethyl]-p...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290965((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290966((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290965((R)-4-Methyl-2-[2-(naphthalene-2-sulfinyl)-ethyl]-...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290963((R)-4-Methyl-2-[2-(naphthalen-2-ylsulfanyl)-ethyl]...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290966((R)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCalpain-1 catalytic subunit(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290964((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity using recombinant human Calpain 1 with Suc-Leu-Tyr-MNA as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290964((S)-4-Methyl-2-[2-(naphthalene-2-sulfonyl)-ethyl]-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity using cysteine protease, Cathepsin B with Cbz-Phe-Arg-AMC as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article