Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50030084
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290968(9H-Fluorene-9-carboxylic acid methyl-((1S,2S)-2-py...)
Affinity DataEC50:  22nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290978(2-(3-Chloro-phenyl)-3-phenyl-cycloprop-2-enecarbox...)
Affinity DataEC50:  141nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290977(2,2-Diphenyl-cyclopropanecarboxylic acid methyl-((...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290976(1-[Methyl-((1S,2S)-2-pyrrolidin-1-yl-cyclohexyl)-c...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290975(2-(3-Methoxy-phenyl)-3-phenyl-cycloprop-2-enecarbo...)
Affinity DataEC50:  300nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290974(N-Methyl-2,2-diphenyl-N-((1S,2S)-2-pyrrolidin-1-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(CI-977 | 2-Benzofuran-4-yl-N-methyl-N-((5R,7S,8S)-...)
Affinity DataEC50:  3.30nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290973(N-Methyl-3,3-diphenyl-N-((1S,2S)-2-pyrrolidin-1-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290972(1-[Methyl-((1S,2S)-2-pyrrolidin-1-yl-cyclohexyl)-c...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290971(2,3-Diphenyl-cycloprop-2-enecarboxylic acid methyl...)
Affinity DataEC50:  32nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290970(2,3-Diphenyl-cyclopropanecarboxylic acid methyl-((...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataEC50:  9.60nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290969(2-(4-Chloro-phenyl)-3-phenyl-cycloprop-2-enecarbox...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(CI-977 | 2-Benzofuran-4-yl-N-methyl-N-((5R,7S,8S)-...)
Affinity DataKi:  0.100nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]U-69593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetKappa-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi:  0.640nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]U-69593 to cloned rat Opioid receptor kappa 1 expressed in CHO cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290967(CI-977 | 2-Benzofuran-4-yl-N-methyl-N-((5R,7S,8S)-...)
Affinity DataKi:  87nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50088375(1-{8-[(2,3-Diphenyl-cycloprop-2-enecarbonyl)-methy...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]DAGO to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article