Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50030135
TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098772(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289945(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291474(3-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-2-sulf...)
Affinity DataIC50: 54nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291481(2-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-3-sulf...)
Affinity DataIC50: 62nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291471(2-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 104nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291476(2-(6-Chloro-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 129nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291480(3-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 134nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291479(2-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-3-sul...)
Affinity DataIC50: 299nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291473(2-(2,4-Dimethyl-phenoxymethyl)-thiophene-3-sulfoni...)
Affinity DataIC50: 308nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291471(2-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 335nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291475(3-(2,4-Dimethyl-phenoxymethyl)-thiophene-2-sulfoni...)
Affinity DataIC50: 346nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291477(3-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-2-sul...)
Affinity DataIC50: 513nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291476(2-(6-Chloro-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 765nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291478(2-p-Tolyloxymethyl-thiophene-3-sulfonic acid (4-br...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291480(3-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thioph...)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291472(3-p-Tolyloxymethyl-thiophene-2-sulfonic acid (4-br...)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291481(2-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-3-sulf...)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291474(3-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-2-sulf...)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291473(2-(2,4-Dimethyl-phenoxymethyl)-thiophene-3-sulfoni...)
Affinity DataIC50: 4.48E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289945(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291479(2-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-3-sul...)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291475(3-(2,4-Dimethyl-phenoxymethyl)-thiophene-2-sulfoni...)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098772(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 8.27E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291477(3-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-2-sul...)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291478(2-p-Tolyloxymethyl-thiophene-3-sulfonic acid (4-br...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291472(3-p-Tolyloxymethyl-thiophene-2-sulfonic acid (4-br...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article