Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50030163
Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataEC50:  150nMAssay Description:Inhibition of forskolin-induced increase in cAMP in human 5-hydroxytryptamine 1A receptor expressed HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164462(2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-hex...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50080166(2-{4-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-yl]-bu...)
Affinity DataKi:  1.20nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016825(CHEMBL421130)
Affinity DataKi:  1.20nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50126474(2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-tet...)
Affinity DataKi:  2.40nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016822(CHEMBL33150)
Affinity DataKi:  2.40nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164454((S)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi:  2.5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016826(CHEMBL34288)
Affinity DataKi:  3.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50023228(CHEMBL33258)
Affinity DataKi:  4.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50126481(2-[4-(1H-Benzoimidazol-4-yl)-piperazin-1-ylmethyl]...)
Affinity DataKi:  4.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  4.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164455((R)-2-[4-((R)-2-Methyl-4-naphthalen-1-yl-piperazin...)
Affinity DataKi:  4.20nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164463((R)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  4.60nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016824(CHEMBL445055)
Affinity DataKi:  5.60nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50126477(2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...)
Affinity DataKi:  5.60nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50023227(CHEMBL2113057)
Affinity DataKi:  6.10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164456((S)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi:  6.30nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164458((R)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi:  6.40nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50126475(2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahyd...)
Affinity DataKi:  6.70nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164462(2-[4-(4-Naphthalen-1-yl-piperazin-1-yl)-butyl]-hex...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  8.90nMAssay Description:In vitro inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50023226(CHEMBL34287)
Affinity DataKi:  9.30nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164457((R)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi:  9.5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016823(CHEMBL430914)
Affinity DataKi:  10nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50126476(2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-tetrahy...)
Affinity DataKi:  10.4nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164459(2-[4-(9H-5,6-Dioxa-benzocyclohepten-1-yl)-piperazi...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164461((S)-2-[4-(9H-5,6-Dioxa-benzocyclohepten-1-yl)-pipe...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cerebral frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164453((S)-2-[4-((S)-2-Methyl-4-naphthalen-1-yl-piperazin...)
Affinity DataKi:  15nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50016825(CHEMBL421130)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164455((R)-2-[4-((R)-2-Methyl-4-naphthalen-1-yl-piperazin...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50078561(CHEMBL416266 | CHEMBL1204203 | Ethanesulfonic acid...)
Affinity DataKi:  27nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164453((S)-2-[4-((S)-2-Methyl-4-naphthalen-1-yl-piperazin...)
Affinity DataKi:  34nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50016822(CHEMBL33150)
Affinity DataKi:  65nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  101nMAssay Description:In vitro inhibition of [3H]5-CT binding to 5-hydroxytryptamine 7 receptor in rat hypothalamus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  192nMAssay Description:In vitro inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50016826(CHEMBL34288)
Affinity DataKi:  348nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi:  976nMAssay Description:In vitro inhibition of [3H]paroxetine binding to 5-hydroxytryptamine transporter in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164454((S)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]GR-113808 binding to 5-hydroxytryptamine 4 receptor of rat striatum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50023226(CHEMBL34287)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50023228(CHEMBL33258)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164459(2-[4-(9H-5,6-Dioxa-benzocyclohepten-1-yl)-piperazi...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164458((R)-2-((S)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164450((S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hex...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50023227(CHEMBL2113057)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50126475(2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahyd...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164461((S)-2-[4-(9H-5,6-Dioxa-benzocyclohepten-1-yl)-pipe...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164457((R)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
LigandPNGBDBM50164456((S)-2-((R)-2-Methyl-4-naphthalen-1-yl-piperazin-1-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2010
Entry Details Article
PubMed
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