Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50034745
TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 1.70nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 82nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 88nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281609(PD-135540 | 1-Pyridin-2-yl-4-[2-(4-pyridin-2-yl-cy...)
Affinity DataIC50: 128nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 202nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataIC50: 238nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281605(PD-135188 | 1-Pyridin-2-yl-4-(4-thiophen-2-yl-cycl...)
Affinity DataIC50: 352nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 412nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 412nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281611(1-Pyridin-2-yl-4-[2-(4-thiophen-2-yl-cyclohex-3-en...)
Affinity DataIC50: 436nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281606(1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...)
Affinity DataIC50: 545nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281606(1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...)
Affinity DataIC50: 545nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281610(1-(4-Phenyl-cyclohex-3-enyl)-4-pyridin-2-yl-pipera...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 704nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281607(1-Pyridin-2-yl-4-(4-pyridin-2-yl-cyclohex-3-enyl)-...)
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281608(PD-135146 | 1-Pyridin-2-yl-4-(4-thiophen-2-yl-cycl...)
Affinity DataIC50: 2.43E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 2.92E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281606(1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyrid...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50055724(PD-137789 | 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-et...)
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article