Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50034770
TargetNeuromedin-K receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 9nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50: 10nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282774({(S)-1-[(R)-1-(8-Carbamoyl-octylcarbamoyl)-2-pheny...)
Affinity DataIC50: 15nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 16nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50052524((S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-m...)
Affinity DataIC50: 21nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282775((S)-2-[2-((S)-2-{(S)-2-[2-(4-Hydroxy-phenyl)-acety...)
Affinity DataIC50: 28nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282774({(S)-1-[(R)-1-(8-Carbamoyl-octylcarbamoyl)-2-pheny...)
Affinity DataIC50: 39nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282777({(S)-1-[1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-ethy...)
Affinity DataIC50: 92nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282783({(S)-1-[1-(8-Methoxy-octylcarbamoyl)-2-phenyl-ethy...)
Affinity DataIC50: 102nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282780(8-[2-((S)-2-tert-Butoxycarbonylamino-2-methyl-3-ph...)
Affinity DataIC50: 229nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282786({(S)-1-[1-(4-Hydroxy-benzylcarbamoyl)-2-phenyl-eth...)
Affinity DataIC50: 425nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282784([(S)-1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-1-met...)
Affinity DataIC50: 1.52E+3nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050675([(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2...)
Affinity DataIC50: 1.55E+3nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282779({(S)-1-[(S)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 1.69E+3nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50282774({(S)-1-[(R)-1-(8-Carbamoyl-octylcarbamoyl)-2-pheny...)
Affinity DataIC50: 5.02E+3nMAssay Description:Binding affinity for NK2 receptor binding sites in membranes prepared from hamster urinary bladder by using [125I]NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282781((S)-N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-hydroxy...)
Affinity DataIC50: 5.89E+3nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 6.16E+3nMAssay Description:Binding affinity for NK2 receptor binding sites in membranes prepared from hamster urinary bladder by using [125I]NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 6.54E+3nMAssay Description:Binding affinity for NK2 receptor binding sites in membranes prepared from hamster urinary bladder by using [125I]NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for NK1 receptor binding sites in human lymphoma IM9 cells by using [125I]-Bolton-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282774({(S)-1-[(R)-1-(8-Carbamoyl-octylcarbamoyl)-2-pheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for NK1 receptor binding sites in human lymphoma IM9 cells by using [125I]-Bolton-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282785([(R)-1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-1-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity for human NK3 receptor expressed in CHO cells by using [125I][MePhe]-NKB as radioligand,More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50050649({(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-ureido-heptylca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for NK1 receptor binding sites in human lymphoma IM9 cells by using [125I]-Bolton-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article