Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50034788
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284094(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284090(Pyrazolo[1,5-a]pyridine-3-carboxylic acid 8-methyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284089(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (8-methy...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284094(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50: 42nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284088(N-[(3R)-1-azabicyclo[2.2.1]hept-3-yl]pyrazolo[1,5-...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284097(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284095(N-[(3S,4R)-1-azabicyclo[2.2.1]hept-3-yl]pyrazolo[1...)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284098(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (1-aza-b...)
Affinity DataIC50: 75nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284098(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (1-aza-b...)
Affinity DataIC50: 83nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284097(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284089(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (8-methy...)
Affinity DataIC50: 105nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284093(2-Methyl-pyrazolo[1,5-b]pyridazine-3-carboxylic ac...)
Affinity DataIC50: 122nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284088(N-[(3R)-1-azabicyclo[2.2.1]hept-3-yl]pyrazolo[1,5-...)
Affinity DataIC50: 124nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284096(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (9-methy...)
Affinity DataIC50: 170nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284096(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (9-methy...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284092(2-Methyl-pyrazolo[1,5-b]pyridazine-3-carboxylic ac...)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284095(N-[(3S,4R)-1-azabicyclo[2.2.1]hept-3-yl]pyrazolo[1...)
Affinity DataIC50: 419nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284099(Pyrazolo[1,5-b]pyridazine-3-carboxylic acid (8-met...)
Affinity DataIC50: 429nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

LigandPNGBDBM50284091(Pyrazolo[1,5-b]pyridazine-3-carboxylic acid (9-met...)
Affinity DataIC50: 818nMAssay Description:Tested for inhibition of binding of [3H]GR-65630 to rat cortical membranes, expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (8-methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284090(Pyrazolo[1,5-a]pyridine-3-carboxylic acid 8-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity for Dopamine D2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(Pyrazolo[1,5-a]pyridine-3-carboxylic acid (8-methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity for Dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284090(Pyrazolo[1,5-a]pyridine-3-carboxylic acid 8-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article