Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50034821
TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045698(WIN-57294 | 1-Cyclopropyl-7-(2,6-dimethyl-pyridin-...)
Affinity DataEC50: >5.40E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  930nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50: >7.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286489(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286490(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286491(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286496(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286488(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286497(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50: >5.10E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286495(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286493([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286499(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286498(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50: >5.20E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286500(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286487([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045706(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50: >5.50E+4nMAssay Description:Inhibition of calf thymus DNA/ethidium bromide complex formation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045706(1-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+4nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50:  900nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286499(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  5.90E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286491(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  3.20E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286489(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  3.10E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286490(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.10E+4nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286497(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50:  9.80E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50:  500nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50045698(WIN-57294 | 1-Cyclopropyl-7-(2,6-dimethyl-pyridin-...)
Affinity DataEC50:  7.60E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286493([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50:  1.00E+4nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286495(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  3.30E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286488(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50:  4.40E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286487([5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-d...)
Affinity DataEC50:  6.10E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286498(N-{4-[5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-...)
Affinity DataEC50:  7.40E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286496(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50:  4.20E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  2.60E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDNA topoisomerase 2-alpha/2-beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286500(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  6.40E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article