Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50034842
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 1.5nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50: 2.5nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 55nMAssay Description:Compound was measured for the inhibition of neutral endopeptidase 24.11(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287440((S)-2-[(1-{[(R)-1-((S)-6-Benzyloxycarbonylamino-2-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287430((S)-2-[(1-{[(R)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50: 90nMAssay Description:Compound was measured for the inhibition of neutral endopeptidase 24.11(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287438((S)-2-[(1-{[(R)-1-(4-Aminomethyl-benzoylamino)-2-p...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287431((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287437((S)-2-[(1-{Hydroxy-[(R)-1-(4-methoxy-benzoylamino)...)
Affinity DataIC50: 160nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287444((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287434((S)-2-({1-[((R)-1-Benzoylamino-2-phenyl-ethyl)-hyd...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287445((S)-2-({1-[(Benzyloxycarbonylamino-methyl)-hydroxy...)
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50251742((S)-2-{(R)-2-[Hydroxy-((2R,3R,4R,5R,6S)-3,4,5-trih...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287442((S)-2-[(1-{[(R)-1-(2,2-Dimethyl-propionylamino)-2-...)
Affinity DataIC50: 550nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287439((S)-2-({1-[((R)-1-Acetylamino-2-phenyl-ethyl)-hydr...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287443((S)-2-({1-[((R)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287436((S)-3-(1H-Indol-3-yl)-2-((S)-4-methyl-2-phosphonoa...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287435((S)-2-[(1-{[(S)-1-((S)-6-Benzyloxycarbonylamino-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287441((S)-2-({1-[((S)-1-Benzyloxycarbonylamino-2-phenyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287433((S)-2-[(1-{[(S)-1-((S)-6-Amino-2-methanesulfonylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article