Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50034904
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 2.5nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 2.60nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 4.30nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50290502(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N,N'-d...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22167(GBR-12935 | CHEMBL26320 | CHEMBL434080 | 1-[2-(dip...)
Affinity DataIC50: 37nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290501(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N'-(3-...)
Affinity DataIC50: 49nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 70nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22418(Cocaine (-) | methyl (1R,2R,3S,5S)-3-(benzoyloxy)-...)
Affinity DataIC50: 89nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290503(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-pro...)
Affinity DataIC50: 150nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22167(GBR-12935 | CHEMBL26320 | CHEMBL434080 | 1-[2-(dip...)
Affinity DataIC50: 290nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290501(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N'-(3-...)
Affinity DataIC50: 500nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290498(1-(2-Benzhydryloxy-ethyl)-4-((E)-3-iodo-allyl)-pip...)
Affinity DataIC50: 505nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290499(1-(2-Benzhydryloxy-ethyl)-4-((Z)-3-iodo-allyl)-pip...)
Affinity DataIC50: 780nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM22418(Cocaine (-) | methyl (1R,2R,3S,5S)-3-(benzoyloxy)-...)
Affinity DataIC50: 1.05E+3nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50048392(BUPROPION HYDROCHLORIDE | CHEMBL894 | 2-(tert-buty...)
Affinity DataIC50: 1.23E+3nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290500(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-eth...)
Affinity DataIC50: 1.23E+3nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290502(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N,N'-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290499(1-(2-Benzhydryloxy-ethyl)-4-((Z)-3-iodo-allyl)-pip...)
Affinity DataIC50: 2.19E+3nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine (-) | methyl (1R,2R,3S,5S)-3-(benzoyloxy)-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290498(1-(2-Benzhydryloxy-ethyl)-4-((E)-3-iodo-allyl)-pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290500(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290503(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-pro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290500(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-eth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290501(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N'-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290503(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-pro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290498(1-(2-Benzhydryloxy-ethyl)-4-((E)-3-iodo-allyl)-pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290502(N-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-N,N'-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

LigandPNGBDBM50290499(1-(2-Benzhydryloxy-ethyl)-4-((Z)-3-iodo-allyl)-pip...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article