Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50034912
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 170nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPH and 1.0 mM inorganic pyrophosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against squalene synthase using rat liver microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 950nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 1.2 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290880([Hydroxy-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-t...)
Affinity DataIC50: 5.00E+3nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50059865([Hydroxy-(4,8,12-trimethyl-trideca-3,7,11-trienyl)...)
Affinity DataIC50: 7.00E+3nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290883(N-hydroxyglycine derivative | CHEMBL102874)
Affinity DataIC50: 1.40E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290887(N-hydroxyglycine derivative | CHEMBL99892)
Affinity DataIC50: 2.10E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290888(N-hydroxyglycine derivative | CHEMBL102520)
Affinity DataIC50: 2.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290881(N-hydroxyglycine derivative | CHEMBL319416)
Affinity DataIC50: 2.90E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290885(N-hydroxyglycine derivative | CHEMBL99944)
Affinity DataIC50: 3.00E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290882(N-hydroxyglycine derivative | CHEMBL102521)
Affinity DataIC50: 5.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290886(N-hydroxyglycine derivative | CHEMBL102570)
Affinity DataIC50: 8.70E+4nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290879([Hydroxy-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-t...)
Affinity DataIC50: 5.23E+5nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290884(((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylami...)
Affinity DataIC50: 6.40E+5nMAssay Description:The compound was tested for inhibition of purified rat hepatic squalene synthase in the presence of 0.025 mM NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article