Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50003590
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027227(3-Methyl-1,2,3,4,4a,8-hexahydro-5-thia-3,12b-diaza...)
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027227(3-Methyl-1,2,3,4,4a,8-hexahydro-5-thia-3,12b-diaza...)
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31005(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31005(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Affinity DataIC50: 20nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50: 100nMAssay Description:In vitro binding affinity of alpha-adrenoceptor by interacting with high affinity, [3H]serotonin from calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31005(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Affinity DataIC50: 300nMAssay Description:In vitro binding affinity of alpha-adrenoceptor by interacting with high affinity [3H]5-HT from calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50: 300nMAssay Description:In vitro binding affinity towards alpha-adreno ceptor of rat forebrain using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027227(3-Methyl-1,2,3,4,4a,8-hexahydro-5-thia-3,12b-diaza...)
Affinity DataIC50: 500nMAssay Description:In vitro binding affinity of alpha-adrenoceptor by interacting with high affinity [3H]5-HT from calf caudate nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM31005(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro binding affinity towards alpha-adreno ceptor of rat forebrain using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027227(3-Methyl-1,2,3,4,4a,8-hexahydro-5-thia-3,12b-diaza...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro binding affinity towards alpha-adreno ceptor of rat forebrain using [3H]prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM31005(MIANSERIN HYDROCHLORIDE | SMR000058472 | MLS000069...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro antihistamine activity by activation of 4-methylhistamine mediated by Histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro antihistamine activity by activation of 4-methylhistamine mediated by Histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50027227(3-Methyl-1,2,3,4,4a,8-hexahydro-5-thia-3,12b-diaza...)
Affinity DataIC50: 1.90E+4nMAssay Description:In vitro antihistamine activity by activation of 4-methylhistamine mediated by Histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed