Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50048636
LigandPNGBDBM50224275(CHEMBL278717)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224275(CHEMBL278717)
Affinity DataIC50: 8nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 14nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224274(CHEMBL2304423)
Affinity DataIC50: 16nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224274(CHEMBL2304423)
Affinity DataIC50: 18nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224277(CHEMBL280309)
Affinity DataIC50: 22nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 22nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224277(CHEMBL280309)
Affinity DataIC50: 26nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 44nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50224276(CHEMBL277122)
Affinity DataIC50: 55nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50224276(CHEMBL277122)
Affinity DataIC50: 90nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 150nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)