Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50048625
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50: 12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 39nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataIC50: 49nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 290nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 342nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50: 610nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataIC50: 622nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 670nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataIC50: 678nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50010594(ISOCLOZAPINE | 2-Chloro-11-(4-methyl-piperazin-1-y...)
Affinity DataIC50: 758nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50: 808nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028980(CHEMBL7828 | Isoloxapine | 8-chloro-11-(4-methylpi...)
Affinity DataIC50: 2.48E+3nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50: 4.31E+3nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50223641(CHEMBL266816)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50: 3.24E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed