Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50005115
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  4.30nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033042(2-[2-(1H-Imidazol-4-yl)-ethylsulfanyl]-5-nitro-pyr...)
Affinity DataKi:  4.80nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033045(1-Cyclohexyl-3-[3-(1H-imidazol-4-yl)-propyl]-thiou...)
Affinity DataKi:  13nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033038([2-(1H-Imidazol-4-yl)-ethyl]-(5-trifluoromethyl-py...)
Affinity DataKi:  17nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033054(1-Cyclohexyl-3-[4-(1H-imidazol-4-yl)-butyl]-thiour...)
Affinity DataKi:  20nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033036([2-(1H-Imidazol-4-yl)-ethyl]-(5-nitro-pyridin-2-yl...)
Affinity DataKi:  29nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033039(6-[2-(1H-Imidazol-4-yl)-ethylamino]-nicotinic acid...)
Affinity DataKi:  42nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033041(4-(1H-Imidazol-4-yl)-5'-trifluoromethyl-3,4,5,6-te...)
Affinity DataKi:  42nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033050([2-(1H-Imidazol-4-yl)-ethyl]-(4-nitro-1-oxy-pyridi...)
Affinity DataKi:  53nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM22888(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | C...)
Affinity DataKi:  70nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033052(2-[2-(1H-Imidazol-4-yl)-ethylsulfanyl]-pyridine | ...)
Affinity DataKi:  92nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033053((2-Chloro-pyridin-4-yl)-[2-(1H-imidazol-4-yl)-ethy...)
Affinity DataKi:  160nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033043([3-(1H-Imidazol-4-yl)-propyl]-(5-nitro-pyridin-2-y...)
Affinity DataKi:  170nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033048(N*2*-[2-(1H-Imidazol-4-yl)-ethyl]-pyridine-2,5-dia...)
Affinity DataKi:  186nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033037([2-(1H-Imidazol-4-yl)-ethyl]-pyridin-2-yl-amine | ...)
Affinity DataKi:  200nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033044([2-(1H-Imidazol-4-yl)-ethyl]-pyrazin-2-yl-amine | ...)
Affinity DataKi:  200nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033047([2-(1H-Imidazol-4-yl)-ethyl]-(3-nitro-pyridin-2-yl...)
Affinity DataKi:  240nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033051(Benzothiazol-2-yl-[2-(1H-imidazol-4-yl)-ethyl]-ami...)
Affinity DataKi:  330nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033055([2-(1H-Imidazol-4-yl)-ethyl]-thiazol-2-yl-amine | ...)
Affinity DataKi:  340nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033056(1H-2-imidazolyl 2-(1H-4-imidazolyl)ethyl sulfide |...)
Affinity DataKi:  400nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033049([2-(1H-Imidazol-4-ylmethylsulfanyl)-ethyl]-(5-nitr...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50033040((2-Pyridin-2-yl-ethyl)-pyrimidin-2-yl-amine | CHEM...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro antagonism of the histamine H3-receptor in the rat cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed