Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50036351
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50: >5.00E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  59nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033115(CHEMBL544814 | CHEMBL2115374 | (5aS,11bR)-2-Propyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  170nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataEC50:  14nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  100nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataEC50:  1.61E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataEC50: >4.00E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033114(2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyc...)
Affinity DataEC50:  9nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033115(CHEMBL544814 | CHEMBL2115374 | (5aS,11bR)-2-Propyl...)
Affinity DataEC50:  1.70E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033114(2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyc...)
Affinity DataEC50:  3.90E+3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataEC50:  3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataKi:  21nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi:  33nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033114(2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyc...)
Affinity DataKi:  49nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataKi:  56nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  130nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  260nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033114(2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyc...)
Affinity DataKi:  710nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity against Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity against Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi:  1.52E+3nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataKi:  1.55E+3nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity against serotonergic 5-HT1c receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against serotonergic 5-HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50010686(dihydrexidine | 10,11-Dihydroxy-5,6,6a,7,8,12b-hex...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against serotonergic 5-HT1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033115(CHEMBL544814 | CHEMBL2115374 | (5aS,11bR)-2-Propyl...)
Affinity DataKi:  3.05E+3nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033115(CHEMBL544814 | CHEMBL2115374 | (5aS,11bR)-2-Propyl...)
Affinity DataKi:  4.02E+3nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataKi:  4.67E+3nMAssay Description:Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed