Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50036396
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034001(CHEMBL1082435 | CHEMBL555075 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 4.30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 6nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034002(CHEMBL542543 | CHEMBL1084275 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 6.80nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034003(CHEMBL542297 | CHEMBL1084790 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 12nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 19nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(CHEMBL1196495 | CHEMBL557181 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034004(CHEMBL537908 | CHEMBL1082436 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 33nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 73nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 267nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033999(CHEMBL552832 | CHEMBL1082433 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 305nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034004(CHEMBL537908 | CHEMBL1082436 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 890nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 2.90E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034002(CHEMBL542543 | CHEMBL1084275 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 3.40E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034001(CHEMBL1082435 | CHEMBL555075 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 4.20E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033999(CHEMBL552832 | CHEMBL1082433 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 4.30E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(CHEMBL1196495 | CHEMBL557181 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 4.80E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034003(CHEMBL542297 | CHEMBL1084790 | 3-(1-Benzyl-piperid...)
Affinity DataIC50: 6.20E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed