Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50005309
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035471(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...)
Affinity DataKd:  2.40nMAssay Description:Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035476(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataKd:  3.40nMAssay Description:Tested for competitive covalent binding of compound against k opioid receptor in guinea pig brain membrane; using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035476(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataIC50: 0.000320nMAssay Description:Binding affinity kappa opioid receptor in guinea pig brain membranes; using 1 nM [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035471(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...)
Affinity DataIC50: 2.20nMAssay Description:Binding affinity kappa opioid receptor in guinea pig brain membranes, using 1 nM [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035476(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataIC50: 31nMAssay Description:Binding affinity for mu opioid receptor in guinea pig brain membranes; using 2 nM [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035476(N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]...)
Affinity DataIC50: 89nMAssay Description:Binding affinity for delta opioid receptor in guinea pig brain membranes; using 2 nM [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035471(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity for delta opioid receptor in guinea pig brain membranes, using 2 nM [3H]DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50035471(2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato...)
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity for mu opioid receptor in guinea pig brain membranes, using 2 nM [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed