Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50036325
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035963(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035955(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035961(1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035961(1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035970(SC-47643 | 3-(8-Guanidino-octanoylamino)-N-[2-(4-m...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035955(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035962(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035960(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035961(1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035960(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035955(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035963(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241180(3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035970(SC-47643 | 3-(8-Guanidino-octanoylamino)-N-[2-(4-m...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035970(SC-47643 | 3-(8-Guanidino-octanoylamino)-N-[2-(4-m...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035956(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035964(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035972(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of thrombin-induced platelet aggregation at 50 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035962(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035960(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241180(3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of arachidonic acid-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035953(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50241180(3-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035954(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035963(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035967(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035957(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035962(5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035959(5-Trifluoromethyl-1-[4-(4-trifluoromethyl-phenyl)-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035968(1-[4-(4-Chloro-phenyl)-thiazol-2-yl]-5-trifluorome...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035958(1-(4-Phenyl-thiazol-2-yl)-5-trifluoromethyl-1H-pyr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035969(1-(4-m-Tolyl-thiazol-2-yl)-5-trifluoromethyl-1H-py...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50035965(1-(4-p-Tolyl-thiazol-2-yl)-5-trifluoromethyl-1H-py...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of collagen-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed