Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50005380
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036261((S)-N*1*-{(1S,2R)-3-[Benzenesulfonyl-(3-methyl-but...)
Affinity DataIC50: 1.5nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036257(((S)-1-{(1S,2R)-3-[Benzenesulfonyl-(3-methyl-butyl...)
Affinity DataIC50: 2.20nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036251([(1S,2R)-3-(Benzenesulfonyl-isobutyl-amino)-1-benz...)
Affinity DataIC50: 6nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036252({(1S,2R)-1-Benzyl-3-[(4-chloro-benzenesulfonyl)-(3...)
Affinity DataIC50: 10nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036262([(1S,2R)-3-(Benzenesulfonyl-cyclohexylmethyl-amino...)
Affinity DataIC50: 14nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036253({(1S,2R)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataIC50: 16nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036259((S)-N*1*-{(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesul...)
Affinity DataIC50: 27nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036260({(1S,2R)-1-Benzyl-3-[(3-chloro-benzenesulfonyl)-(3...)
Affinity DataIC50: 92nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036258(((S)-1-{(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesulfo...)
Affinity DataIC50: 100nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036255([(1S,2R)-3-(Benzenesulfonyl-benzyl-amino)-1-benzyl...)
Affinity DataIC50: 190nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036254({(1S,2R)-1-Benzyl-2-hydroxy-3-[(3-methyl-butyl)-(p...)
Affinity DataIC50: 210nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036264({(1S,2R)-1-Benzyl-3-[(2-chloro-benzenesulfonyl)-(3...)
Affinity DataIC50: 380nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036263({(1S,2S)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataIC50: 450nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036256({(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesulfonyl-(3-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036265({(1S,2R)-1-Benzyl-2-hydroxy-3-[(3-methyl-butyl)-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036257(((S)-1-{(1S,2R)-3-[Benzenesulfonyl-(3-methyl-butyl...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036261((S)-N*1*-{(1S,2R)-3-[Benzenesulfonyl-(3-methyl-but...)
Affinity DataKi:  1nMAssay Description:Binding affinity for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036251([(1S,2R)-3-(Benzenesulfonyl-isobutyl-amino)-1-benz...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036252({(1S,2R)-1-Benzyl-3-[(4-chloro-benzenesulfonyl)-(3...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036262([(1S,2R)-3-(Benzenesulfonyl-cyclohexylmethyl-amino...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036253({(1S,2R)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataKi:  10nMAssay Description:Binding affinity for HIV-1 protease was determined in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036259((S)-N*1*-{(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesul...)
Affinity DataKi:  13nMAssay Description:Binding affinity for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036258(((S)-1-{(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesulfo...)
Affinity DataKi:  57nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036260({(1S,2R)-1-Benzyl-3-[(3-chloro-benzenesulfonyl)-(3...)
Affinity DataKi:  61nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036255([(1S,2R)-3-(Benzenesulfonyl-benzyl-amino)-1-benzyl...)
Affinity DataKi:  125nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036254({(1S,2R)-1-Benzyl-2-hydroxy-3-[(3-methyl-butyl)-(p...)
Affinity DataKi:  128nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036264({(1S,2R)-1-Benzyl-3-[(2-chloro-benzenesulfonyl)-(3...)
Affinity DataKi:  227nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036263({(1S,2S)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataKi:  295nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036256({(1S,2R)-1-Benzyl-2-hydroxy-3-[methanesulfonyl-(3-...)
Affinity DataKi:  1.87E+3nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed