Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50005415
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.330nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  1.80nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  2.20nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036735((R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  33nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036733(1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036733(1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036737((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi:  64nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036732((S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036732((S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036732((S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  183nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  279nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036734((S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036733(1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-...)
Affinity DataKi:  342nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036735((R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  374nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036735((R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazi...)
Affinity DataKi:  403nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036736((S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi:  490nMAssay Description:Tested for [3H](+)-pentazocine binding to sigma-1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036738((R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-h...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036736((S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036737((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-spiperone from CHO-K1 cell membranes expressing human dopamine 3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036736((S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi:  3.35E+3nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50036737((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]spiperone from CHO-K1 cell membranes expressing human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed